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Retinol vs Hyaluronic Acid: Expert Guide to Choosing the Right Skincare Ingredient

other · 2026-08-28

Vogue has released a comparison of retinol and hyaluronic acid (HA) for skincare. Dr. Maryam Zamani and Dr. Ariel Haus provide insights, noting that HA acts as a humectant ideal for dehydrated skin, while retinol, a derivative of vitamin A, enhances cell turnover and collagen production, addressing fine lines, acne, and pigmentation issues. HA delivers instant hydration, whereas retinol focuses on long-term improvements. Retinol is favored for fine lines and acne, while HA is beneficial during retinol application. For hyperpigmentation, retinol is effective, but the use of SPF and vitamin C is essential. HA is suitable for everyone, while retinol is recommended for those in their mid-to-late twenties dealing with photoaging or texture. Both can be combined, with HA applied prior to retinol. Suggested products include Medik8 Crystal Retinal 1 Serum and SkinCeuticals H.A. Intensifier.

Key facts

  • Hyaluronic acid is a humectant that binds 1000 times its weight in water, ideal for dehydrated skin.
  • Retinol is a vitamin A derivative that increases cell turnover and stimulates collagen, addressing fine lines, acne, and pigmentation.
  • Dr. Ariel Haus: 'Hyaluronic acid gives the skin water; retinol gives the skin instructions.'
  • Retinol requires two conversions to become retinoic acid, the biologically active form.
  • Retinol should be used in the evening and followed by SPF the next day.
  • Both ingredients can be used together; HA helps reduce retinol irritation.
  • Beginners should start with 0.1-0.3% retinol, twice a week, building up over 8-12 weeks.
  • Dr. Maryam Zamani recommends a broad-spectrum SPF every morning when using retinol.
  • For hyperpigmentation, retinol alone is not enough; SPF and other ingredients like vitamin C are needed.
  • Hyaluronic acid should be applied to damp skin and sealed with a moisturizer.

Entities

Artists

  • Dr. Maryam Zamani
  • Dr. Ariel Haus

Institutions

  • Vogue
  • Dr. Haus Dermatology
  • Medik8
  • SkinCeuticals
  • Vichy
  • Isdin
  • L'Oreal Paris
  • The Ordinary

Locations

  • Harley Street
  • London
  • United Kingdom

Sources