Dermatologists Explain Adapalene: The OTC Retinoid for Acne Treatment and Prevention
According to dermatologist Sonia Badreshia, Adapalene is a retinoid used for acne that helps regulate cell turnover and prevents pore blockages. Marisa Garshick notes that it is more photostable and gentler than other retinoids, requiring no skin adaptation. Hadley King points out its quick results and anti-inflammatory effects. Adapalene effectively addresses blackheads, whiteheads, inflammatory acne, uneven skin texture, and post-acne scars, although it may lead to dryness and irritation. It is not advisable for use during pregnancy or breastfeeding. Now available over the counter in 0.1% formulations, options include La Roche-Posay Effaclar Gel and Neutrogena Evenly Clear Gel. Begin with a pea-sized amount every other night, and exercise caution when using with benzoyl peroxide or salicylic acid unless combined, as in Differin Epiduo. For serious cases, consulting a dermatologist is recommended.
Key facts
- Adapalene normalizes cell turnover to prevent clogged pores rather than treating individual breakouts
- Adapalene does not need conversion by the skin to become active and is gentler than tretinoin
- Adapalene is more photostable than other retinoids and can be used during the day
- 0.1% adapalene concentrations are approved for over-the-counter use; higher concentrations require a prescription
- Common side effects include dryness, redness, peeling, burning, and irritation
- Adapalene is not recommended for pregnant or breastfeeding individuals
- Differin Epiduo combines adapalene and benzoyl peroxide and was approved this past May for OTC use
- Experts recommend a pea-sized amount applied after cleansing and before moisturizing, starting every other night
Entities
Artists
- Sonia Badreshia
- Marisa Garshick
- Hadley King
Institutions
- Vogue
- Elite MD
- MDCS Dermatology
- La Roche-Posay
- Neutrogena
- PanOxyl
- SkinFix
- Differin
Locations
- New York City
- United States