Collagen Tripeptides: Dermatologist Weighs In on the Newest Supplement Form

Collagen tripeptides, the tiniest fragments of collagen, are being promoted for their superior absorption and ability to enhance the body’s collagen production compared to previous supplements. According to dermatologist Dr. Derrick Phillips, these tripeptides consist of only three amino acids, setting them apart from standard collagen peptides that feature a broader range of fragment sizes. Due to their minimal size, some tripeptides can enter the bloodstream intact, while others may decompose into dipeptides and single amino acids. Research has shown the presence of collagen-derived tripeptides and dipeptides in the blood post-consumption, alongside lab findings suggesting these peptides might affect fibroblasts, the skin cells responsible for collagen synthesis. Collagen constitutes about 30% of the body’s protein and is vital for skin, bones, and connective tissues, but its natural production starts to decline in the mid-20s, impacting firmness and joint health. A writer from Vogue shares her months-long experience with various collagen forms, including marine and bovine sources, expressing uncertainty about their effectiveness and absorption. Vogue encourages readers to submit beauty and wellness trend ideas to beauty@vogue.com.