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Systematic Review of Task-Aligned Self-Supervised Learning in Medical Imaging

publication · 2026-05-26

A systematic review examining 75 studies published between 2017 and 2025 has been released, focusing on task-aligned self-supervised learning (SSL) in medical imaging. Organized into four paradigms—contrastive, non-contrastive and predictive, generative and reconstruction-based, and hybrid learning—the review adheres to PRISMA guidelines. It correlates each paradigm with downstream objectives, such as classification, segmentation, and detection. Notably, there is no single optimal SSL strategy; effectiveness varies based on task alignment. The study also offers design guidelines for SSL in medical imaging and is accessible on arXiv under ID 2605.23995.

Key facts

  • The review analyzes 75 studies published between 2017 and 2025.
  • SSL methods are organized into four paradigms: contrastive, non-contrastive and predictive, generative and reconstruction-based, and hybrid learning.
  • The review follows PRISMA guidelines.
  • The study maps each paradigm to downstream objectives like classification, segmentation, and detection.
  • No universally optimal SSL strategy exists; performance depends on task alignment.
  • The review provides practical design guidelines for SSL in medical imaging.
  • The paper is available on arXiv with ID 2605.23995.
  • The review is task-oriented, focusing on pretext task design and clinical objective alignment.

Entities

Institutions

  • arXiv

Sources