Russian Study Proposes Human Lifespan Could Reach 156 Years

In a recent study published in the journal npj Aging, Russian scientists Evgeniy Efimov, Vlad Fedotov, and Leonid Malaev propose that humans might have the potential to live as long as 156 years. They developed a multistage mathematical model to explore aging processes, revealing that somatic mutations in non-renewing tissues, particularly neurons and cardiomyocytes, primarily constrain lifespan. By removing all other aging factors, these mutations lowered the theoretical median lifespan from 1,759 years to 156. Tissues with significant regenerative abilities, such as the liver, could endure for thousands of years. The researchers emphasize the importance of investigating somatic mutations and non-regenerative tissues, intending to add more aging variables and expand their model to other species.