ARTFEED — Contemporary Art Intelligence

NeuroAPS-Net: Lightweight AI Model for Alzheimer's Classification

ai-technology · 2026-04-29

Researchers have developed NeuroAPS-Net, a lightweight geometric deep learning model for Alzheimer's disease classification using structural MRI. The model converts T1-weighted MRI into anatomically informed 2D point clouds via Anatomical Priority Sampling (APS), creating the ADNI-2DPC dataset—the first neuroanatomically labeled MRI-derived point cloud dataset. NeuroAPS-Net incorporates anatomical priors through region-aware feature encoding and ROI token aggregation. Experiments show competitive classification accuracy with significantly reduced inference latency and GPU memory compared to traditional 3D CNNs, enabling deployment in resource-constrained settings.

Key facts

  • NeuroAPS-Net is a lightweight geometric deep learning model for Alzheimer's classification.
  • It uses Anatomical Priority Sampling (APS) to convert T1-weighted MRI into 2D point clouds.
  • The ADNI-2DPC dataset is the first neuroanatomically labeled MRI-derived point cloud dataset.
  • NeuroAPS-Net incorporates region-aware feature encoding and ROI token aggregation.
  • The model achieves competitive accuracy with lower inference latency and GPU memory usage.
  • The work addresses limitations of computationally expensive 3D CNNs.
  • Alzheimer's disease is a progressive neurodegenerative disorder and major cause of dementia.
  • Structural MRI is widely used to analyze AD-related brain atrophy.

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