Midlife Vascular Health Linked to 13 Extra Dementia-Free Years
A recent study published in Neurology Open Access reveals that steering clear of high blood pressure, diabetes, and smoking between the ages of 45 and 65 can postpone the onset of dementia by almost 13 years. Over a span of 26 years, researchers evaluated health records from 12,409 individuals. Those who managed to avoid all three risk factors enjoyed an average of 12.6 extra years without dementia. Specifically, women with all three conditions maintained their dementia-free status for 18.1 years, while men averaged 16.6 years. White participants experienced an average of 19.6 years, in contrast to 16 years for Black participants. Epidemiologist Josef Coresh from NYU Langone Health highlighted the importance of targeted prevention for groups such as Black adults. The study accounted for various factors and underscores the necessity for earlier interventions, with future research set to investigate the impact of modifying these risk factors on dementia outcomes.
Key facts
- Study published in Neurology Open Access
- Analyzed 12,409 participants over median 26 years
- Avoiding high blood pressure, diabetes, and smoking in midlife adds 12.6 dementia-free years
- Key window: ages 45-65
- Women with all three risks: 18.1 dementia-free years; men: 16.6
- White participants: 19.6 years; Black participants: 16 years
- Controlled for APOE4 gene and other factors
- Josef Coresh of NYU Langone Health is a co-author
Entities
Institutions
- Neurology Open Access
- NYU Langone Health
Locations
- United States
- China