ARTFEED — Contemporary Art Intelligence

Knee-xRAI: Explainable AI Framework for Knee Osteoarthritis Grading

ai-technology · 2026-04-29

Knee-xRAI is a modular AI framework for automatic Kellgren-Lawrence grading of knee osteoarthritis. It independently quantifies joint space narrowing, osteophytes, and subchondral sclerosis using U-Net++ segmentation, SE-ResNet-50, and a hybrid texture-CNN classifier. The structured feature vector feeds XGBoost and ConvNeXt paths for explainable classification. The framework addresses inter-reader variability and opacity in deep learning approaches.

Key facts

  • Knee-xRAI is a modular framework for KL grading of knee osteoarthritis.
  • It quantifies three cardinal features: JSN, osteophytes, and subchondral sclerosis.
  • Uses U-Net++ for JSN measurement, SE-ResNet-50 for osteophyte grading, and hybrid texture-CNN for sclerosis.
  • Generates a 50-dimensional structured feature vector.
  • XGBoost path supports SHAP-based feature attribution.
  • ConvNeXt hybrid path combines structured features.
  • Aims to reduce inter-reader variability and improve explainability.
  • Published on arXiv with ID 2604.23435.

Entities

Institutions

  • arXiv

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