AI Co-Scientist Helps Calico Unravel Aging Mysteries
Calico Life Sciences, a research firm supported by Alphabet, is leveraging Google's Co-Scientist AI to enhance studies on aging. Matt Onsum, the AI/ML lead, along with principal scientist Katherine Labbé, utilizes this multi-agent system to link disparate insights in aging biology and formulate testable hypotheses. The AI has garnered attention from experts for its ability to navigate through varying quality literature effectively. Notably, Co-Scientist contributed to a new hypothesis regarding the regulation of the integrated stress response (ISR) by metabolism, which alters with age. The team refined their experimental approach using AI-generated insights and incorporated new data, revealing significant implications for ISR in health and disease. They aim to publish their findings, with Labbé remarking that the AI "thinks like a scientist" and Onsum describing the effort to unravel aging as "a moonshot."
Key facts
- Calico Life Sciences uses Google's Co-Scientist AI for aging research.
- Matt Onsum is head of AI/ML at Calico.
- Katherine Labbé is principal scientist at Calico.
- Co-Scientist helps generate testable hypotheses from scattered biology findings.
- The AI impressed with its scientific discernment.
- A hypothesis was generated about ISR regulation by metabolism.
- Experiments led to new findings on ISR in health and disease.
- Calico plans to publish the results.
Entities
Institutions
- Calico Life Sciences
- Alphabet