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DNA Solves 439-Year-Old Medici Deaths

cultural-heritage · 2026-07-16

DNA evidence has resolved the 1587 deaths of Grand Duke Francesco I de' Medici and his wife Bianca Cappello, ruling out assassination by Francesco's brother Ferdinando. The couple died of malaria, not poison, ending centuries of speculation.

Key facts

  • Francesco I de' Medici and Bianca Cappello died within hours of each other in 1587
  • They suffered days of agony before death
  • Rumors blamed Francesco's brother Ferdinando for assassination
  • DNA evidence reveals malaria as the cause of death
  • The mystery persisted for over 400 years
  • The findings were reported by CNN via MSN

Entities

Artists

  • Francesco I de' Medici
  • Bianca Cappello
  • Ferdinando de' Medici

Institutions

  • CNN
  • MSN

Sources